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In a further embodiment, R 7a is methoxy and R 7d is substituted N-piperidinylmethyl, R 7a is halogen ( eg, fluorine) and R 7d is substituted N-piperidinylmethyl or R 7a is methoxy and R 7d is arylalkyl substituted alkylaminoalkyl, such as phenylmethyl substituted alkylaminoalkyl In another embodiment, R 7e and R 7a, R 7b and R 7c are each hydrogen. An amount SnBu 3H (32g, 11mmol) was added via syringe pump over 2 hours! Excuse me, Craig, but “a load of hogwash” is those Guardian articles!

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